Has anyone had much experience with using SS for the creation of an application with a large amount of personalized information per user, and a moderate amount of users?

I'm talking around 10k users accessing the site in varying bursts during the day. Peak concurrent users is around 1000. It's a rather limited membership market, and not expected to explode.

But these users will predominately using the application for viewing and interacting with quite complex data models that are unique to each user. Think of a portal handling and tracking historical financial data.

I have no problem recommending SS for that sort of traffic. It's that the content displayed for each user will be different in places. Sometimes greatly. And while I've implemented SS for high traffic sites before (I don't consider this traffic high), how the framework will handle many unique queries is a bit grey.

Cheers for any leads.